Movement and positional control of mitochondria and other organelles are coordinated with cell cycle progression in the budding yeast, Saccharomyces cerevisiae. Recent studies have revealed a checkpoint that inhibits cytokinesis when there are severe defects in mitochondrial inheritance. An established checkpoint signaling pathway, the mitotic exit network (MEN), participates in this process. Here, we describe mitochondrial motility during inheritance in budding yeast, emerging evidence for mitochondrial quality control during inheritance, and organelle inheritance checkpoints for mitochondria and other organelles.

In the December-1989 issue of Analog, I wrote an AV Column entitled “Cold Fusion, Pro-fusion, and Con-fusion” that described and gave my opinions about the recently announced “discovery of cold fusion” by Stanley Pons and Martin Fleischmann. These University of Utah electro-chemists claimed that by electrolyzing D2O on a tabletop, they had produced the nuclear fusion of deuterium nuclei.

In this work, on the one hand, we examined the relationship between emotional intelligence (EI) and empathy and, on the other, the relationship between emotional intelligence and nonverbal sensitivity, through two independent studies. The first study analyzed the relationship between dimensions of emotional intelligence and aspects of empathy, in a sample of 856 participants who completed two measures of EI, the Trait Meta-Mood Scale (TMMS) and the Trait Emotional Intelligence Questionnaire (TEIQue), and a measure of empathy, The Interpersonal Reactivity Index (...) (IRI). The results showed a similar pattern of significant positive relations in all the EI domains with empathic Perspective-taking, and significant negative relationships with empathic Personal Distress, except for the EI domain of Attention, which had a positive relationship. Stepwise multiple regression analyses showed that the dimension that best predicted empathic Perspective-taking and Empathic Concern was the Emotionality Factor; whereas Attention best predicted empathic Fantasy; and the Self-Control Factor best predicted Personal Distress, although negatively. Gender emerged as a predictor of three empathic aspects, Fantasy, Empathic Concern, and Personal Distress, with women obtaining higher scores than men in all of them. Age was the only predictor of Fantasy, with a negative relationship. The second study involved 646 people who completed the same measures of EI as the participants of the first study and the Mini-Profile of Nonverbal Sensitivity (Mini-PONS). The results showed some significant relationships between EI dimensions and the channels and quadrants of the MiniPONS. Stepwise multiple regression analyses showed that very few EI dimensions predicted nonverbal sensitivity, with Attention obtaining the best result. Both gender and age emerged as predictors, some in unique cases, of channels, quadrants and of the total score of nonverbal sensitivity; age had a negative relationship, and women obtained higher scores than men. (shrink)

The author presents and defends three theses: (1) "the first is that it is not profitable for us at present to do moral philosophy; that should be laid aside at any rate until we have an adequate philosophy of psychology." (2) "the second is that the concepts of obligation, And duty... And of what is morally right and wrong, And of the moral sense of 'ought', Ought to be jettisoned if this is psychologically possible...." (3) "the third thesis is that (...) the differences between the well-Known english writers on moral philosophy from sidgwick to the present day are of little importance." (staff). (shrink)

This book offers an introduction to the Sophists of fifth-century Athens and a new overall interpretation of their thought. Since Plato first animadverted on their activities, the Sophists have commonly been presented as little better than intellectual mountebanks - a picture which Professor Kerferd forcefully challenges here. Interpreting the evidence with care, he shows them to have been part of an exciting and historically crucial intellectual movement. At the centre of their teaching was a form of relativism, most famously expressed (...) by Protagoras as 'Man is the measure of all things', and which they developed in a wide range of views - on knowledge and argument, virtue, government, society, and the gods. On all these subjects the Sophists did far more than simply provoke Plato to thought. Their contributions were substantial and serious; they inaugurated the debate on many central philosophical questions and decisively shifted the focus of philosophical attention from the cosmos to man. (shrink)

Este artículo analiza cómo los modelos de producción y de consumo de los años veinte determinaron la obsesión cultural por la autenticidad. A partir de los análisis que hicieron Benjamin, Adorno y Kracauer se analiza el modo en que la industria cultural favorece la identificación estética con las estrellas de la conocida como sociedad de masas. A continuación, se explica por qué el origen de esta realidad hay que buscarlo en el proyecto literario y político de Rousseau y en el (...) modo en que éste, al mismo tiempo que rehabilita la novela en la institución literaria, asocia virtud moral y pasión natural. (shrink)

Le droit applicable à l’exercice de l’autorité parentale a été remanié par la loi du 4 mars 2002. Il existe désormais un statut légal du couple parental, applicable quelle que soit la situation familiale des parents, conditionné par l’établissement du lien de filiation de l’enfant. Ce droit commun est gouverné par un principe supérieur : les père et mère exercent en commun l’autorité parentale. La consécration progressive d’un principe d’autorité parentale conjointe (1970,1987,1993, 2002) est certes un progrès en ce qu’elle (...) invite les parents à s’accorder et à se consulter dans l’exercice de l’autorité parentale, mais l’indifférenciation des situations familiales sur laquelle repose désormais la notion de « coparentalité » est excessive en ce qu’elle conduit à détacher le principe du modèle d’un couple uni. Une autre orientation pourrait être prise : celle consistant à rapprocher du mariage le concubinage avec vie maritale, ce qui supposerait de prendre en la matière le contre-pied de la loi de 1999. L’apport le plus apparent de la loi du 4 mars 2002 est de prévoir tout un arsenal de dispositions de nature à assurer l’effectivité du principe de coparentalité, en particulier les conventions et la résidence alternée. Les conventions marquent, sous l’angle de la notion d’ordre public, l’avènement du pluralisme familial, nouveauté encadrée par un corps de règles de plus en plus tentaculaire. Quant à la résidence alternée, cette modalité présente le défaut majeur d’être désormais légale, ce qui implique sa vocation à s’appliquer à tous. Il serait souhaitable pour cette raison de rétablir dans la loi le principe de la résidence habituelle de l’enfant chez l’un de ses parents et de réserver la résidence alternée à la pratique judiciaire, à titre très exceptionnel et expérimental, pour des enfants en âge de l’assumer. (shrink)

El artículo tiene por objeto analizar la construcción del conocimiento mapuche según el discurso de kimches. Sostenemos que en la educación familiar existe un proceso de construcción de conocimientos propios como un sistema de saberes y contenidos educativos para la formación de personas. La metodología empleada es la investigación educativa. Los resultados parciales muestran una descripción acerca de la lógica de los conocimientos educativos propios, para contextualizar la enseñanza y el aprendizaje de las ciencias en el medio escolar, desde la (...) educación intercultural en contexto mapuche. The aim of this article is to analyze the construction of Mapuche knowledge based on the kimches speech. We argue that within family education, there exists a process of constructing their own knowledge, as a system of knowledge and educational contents for forming individuals. The research methodology applied corresponds to education research. Preliminary results describe the logic of individual educational knowledge from intercultural education in the Mapuche context, so as to contextualize the teaching and learning of Science in schools. (shrink)

Deals with the topic of causality. This book traces the evolution of causal thinking from antiquity to the present and culminates with a description of five key conditions that must be satisfied to demonstrate a causal effect.

Face à la violence, que peut la philosophie? Cette question se pose avec une terrible acuité après les attentats de janvier contre Charlie Hebdo et l'hyper-cacher. Le présent ouvrage prétend y apporter une réponse en prenant du recul et à travers la philo française contemporaine de Sartre à Levinas en passant par Camus, Maurice Merleau-Ponty, Simone Weil, Canguilhem, Cavaillès, Lévi-Strauss, Deleuze, Foucault, Jankélévitch et Derrida. Sartre, c'est à la fois l'être et le néant et toutes les questions politiques de l'après-guerre (...) ; Camus, l'absurde et la révolte avec le refus de la violence ; Merleau-Ponty, la justification du communisme et donc d'une certaine forme de totalitarisme ; Simone Weil, Canguilhem et Cavaillès mettent le pacifisme à l'épreuve et en avant l'expérience de la nécessité ; Lévi-Strauss pose le problème de la violence face à la diversité humaine repensée ; Deleuze confronte la métaphysique à la politique. Foucault souligne l'enfermement intolérable ; Jankélévitch Derrida et Levinas pose le problème de l'éthique et de la métaphysique et de l'impossible pardon face au génocide juif. Ici c'est toute la philosophie c'est-à-dire, l'action et la pensée les oeuvres et les relations, l'histoire et l'actualité qui tentent de répondre à une certaine folie du monde. (shrink)

An examination of verbal hallucinations and thought insertion as examples of "alienated self-consciousness.".

This book traces the intellectual revolution initiated by Thales in the sixth century BC to its culmination in the metaphysics of Parmenides.

This paper argues that satire constitutes a particularly effective strategy for feminist philosophy through an analysis of Simone de Beauvoir’s account of motherhood. Feminists have grappled at length with how to interpret Beauvoir’s focus on the unpleasantness of pregnancy and challenges of motherhood. In this paper, I suggest a new interpretive strategy. My view is that Beauvoir’s disparaging depiction of motherhood cannot be read by the letter; rather, it is an exercise in satire. By overemphasizing its strangeness and difficulty, Beauvoir (...) dethrones motherhood as the pinnacle of feminine existence, transforming it from women’s only possible destiny into a contingent feature of existence. My underlying contention here is that such feminist satirizing speaks to the aims of feminist philosophy more generally: the satirical subversion of our buried assumptions opens the possibility of imagining the world anew. (shrink)